The biologically active compounds which are artificially synthesized in laboratories are termed as Steroids, which are of several types. Almost all steroids have the same four-ringed chemical structure, the only difference which differentiates their different types is the length and composition of the carbon chain, attached with the fourth ring. Before starting to use them, you should know how do anabolic steroids work?
These
compounds have a vital role in bodybuilding, and no one can deny it. But if you
think that steroids are like magic pills or injections that can transform your
body into a perfectly shaped muscular body, overnight then you are daydreaming.
You must realize that you are not living in a fantasy world. As every happening
has a reason behind it, in the same way, there is a complete mechanism of
steroid action in your body.
Steroids
do not act immediately, but they have a proper mechanism by which they enter
into your body and perform their function. If you want to get the maximum
results, you should be aware of this mechanism, as steroids alone could do
nothing except damage to your body. A complete diet and proper workout are
necessary for their better result.
By
knowing the mechanism, you will realize how steroids can actually help you.
However, bear in mind the process may vary with regards to the type of
steroids. For example, there’s a difference between testosterone and steroids; thus, they may work differently.
Generally,
these are the following steps of the mechanism of steroids’ action.
Entry into the Body
This
is the first step of the mechanism, as steroids can do nothing without entering
your body. You can intake them by various methods depending upon your need. For
the cure of diseases, they can be entered as inhalers or nasal sprays. But for
muscle development, they are taken as pills, syrups, or injections
Entry into the body system
After
entering the body, the next step is to enter into the cells and tissues that
form the whole body system. Certain protein receptors are present in the body.
Steroids enter into the targeted tissues and cells after combining with these
specialized receptors. Some people might think that the steroid-specific
receptors are similar to the gonadotropin receptors. But in actuality, this is
not true as the receptor specific gonadotropin is only present in the cell
membrane and has several second messengers, systematic receptors.
Interaction with Nucleus
The
most important step which enables steroids to exert their action is the
Steroid-receptor complex retention in the nucleus. To understand this point,
just take an example of estrogen that is responsible for uterine growth, it
fails to cause Nuclear accumulation for six hours or more and they will not be
able to produce true uterine growth. Thus, for the expression of Steroid
activity, the time period for nucleus retention is equally important along with
the production of RNA.
Transcription
Intracellular
Steroid-receptor complex and targeted DNA association lead to the activation of
production of Ribonucleic acid, which is a specific messenger in the target
cell. As a result of this step mRNAs are produced which are transported to the
cytoplasm, where mRNA receive a message from the brain in the form specific
sequences and transfer it to tRNA, now tRNA transport this information to rRNA
which read the sequence and instruct the ribosomes and as result proteins are
synthesized. As a result of Protein
synthesis, the cell growth or physiology, which is the Characteristic of that
steroid for targeted tissue, will be altered and the person will get the
desired results.
Relation With Workout
During
the specific bodybuilding workout, the muscle fibers tear apart. So these
tearing points become the target points. Proteins formed will help to repair
them, testosterone hormone itself is helpful for their recovery. This recovery
process will produce type 1 and 2 muscle fibers, which will make them bigger.
Without workout, no fiber breakage will take place and steroids could randomly
add mass to your body, causing it to de-shape.
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